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IFN alpha 2a (Lys46) (Active) Protéine

Protéine Recombinant exprimée dans Escherichia coli (E. coli).
N° du produit ABIN1096849

Aperçu rapide pour IFN alpha 2a (Lys46) (Active) Protéine (ABIN1096849)

Antigène

IFN alpha 2a

Type de proteíne

Recombinant

Activité biologique

Active

Origine

Humain

Source

  • 1
  • 1
Escherichia coli (E. coli)

Application

Functional Studies (Func)

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Attributs du protein

    Lys46

    Fonction

    Recombinant Human Interferon α2A Variant (Lys46)/IFN-α2A

    Séquence

    MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

    Attributs du produit

    Recombinant Human Interferon-alpha2A/IFN-alpha2A produced in E. coli is a single non-glycosylated polypeptide chain containing 165 amino acids with a molecular mass of 19,241 Daltons.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Commentaires

    Biological activity: Specific Activity is greater than 1.0 x 108 IU/ mg as determined in a viral resistance assay using VSV-WISH cells.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    Conseil sur la manipulation

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Stock

    4 °C/-20 °C/-80 °C

    Stockage commentaire

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Date de péremption

    3 months
  • Antigène

    IFN alpha 2a

    Autre désignation

    IFN-alpha 2a

    Sujet

    At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
    Alternative Names: Interferon Alpha-2, IFN-Alpha-2, Interferon Alpha-A, LeIF A, IFNA2

    Poids moléculaire

    19.24 kDa

    UniProt

    P01563
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